The most common pain relievers that are prescribed for patients across the entire world are opioids. They have got the potential to act several types of endogenous receptors present in the human body called delta (∂), kappa (k), and mu (μ). Opioids are generally safe and incredibly effective at relieving pain but they have a higher addictive potential that can make you dependent on them. Prolonged exposure to opioids may cause side effects such as vomiting & nausea, liver damage, as well as constipation. In some cases, long-term abuse of opioids may even result in death.
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Opioids: Is There a Genuine Alternative?
Because of the adverse side effects and lack of adequate relief of opioids, people with chronic disorders or symptoms are now looking for alternative medications that can be used for long periods without causing any serious effect. In recent years, studies have found that CBD (Cannabidiol) oil could be a safe and effective alternative option to the use of opioids.
CBD isn’t a psychoactive product and once it’s ingested, this cannabis-based product interacts with the body’s endocannabinoid system, a network of various cannabinoid receptors spread throughout the body, controlling appetite, pain resistance, mood, and memory.
CBD oil, a pleiotropic drug, has a range of molecular pathways. Consuming them at t high concentrations will stimulate the 5-HT1A receptor—which leads to an anti-depressant-like effect. The serotonin receptor also takes part in different biological as well as neurological processes, including anxiety, appetite, and pain perception.
The Way Forward?
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CBD oil has become an increasingly popular alternative medication that’s available as pills, creams, or gels. However, CBD isn’t available to everyone and before taking it, medical consultation is highly recommended.
Source: Cannabis and Cannabinoids (PDQ?)?Health Professional Version – National Cancer Institute.
Opioid medications are commonly prescribed as pain relievers for a series of main pain conditions. However, these medications are often linked to addiction, overdose, as well as withdrawal. According to research, cannabis is a much safer as well as an effective alternative to opioid.
Opioids come from a plant known as opium. Opioids are used to reduce pain and they do this by binding itself to the opioid receptors. Cannabis is a natural plant consisting of cannabinoids that produce an extensive range of effects in the human body. The Drug Enforcement Agency (DEA) lists numerous opioids including heroin and all cannabis, cannabinoids, plus hemp products as schedule 1 medications. So, what differentiates opioids from CBD oil, and why should you opt to treat your pain with either of these products?
Opioids and Chronic Pain
Opioids belong to a class of pharmaceutical drugs that are prescribed to deal with chronic pain resulting from illegal substances such as heroin.
Opioids binds to an opioid receptor in certain parts of the human body, including the brain as well as the spinal cord. They (Opioids) trigger the brain receptor sites, which help alleviate the pain signaling messages that come from other parts of the body to the brain. Thus, the pain sensations is alleviated. That’s why opioids are usually prescribed for easing chronic & constant pain cases. Codeine, fentanyl, and hydrocodone in addition to hydromorphone & methadone not forgetting morphine are common types of opioids.
Opioids come with some potential side effects, including constipation, nausea/queasiness, vomiting plus constipation. A patient has a likelihood of developing opioids medication tolerance, which means he/she needs more of it achieve the anticipated effects. Even though opioids can manage pain, the outcome comes at a cost. These medications are often associated with cases of addiction as well as lethal overdoses, even if you are taking it in doctor-recommended dosages.
Perhaps you have heard of several opioids such as morphine, fentanyl, codeine, oxycodone, as well as hydrocodone. They’re a group of drugs which interact with opioid receptors existent in the brain’s nerve cells, responsible for producing euphoric and pain relieving effects. According to medical studies, both the usage of prescription opioids and an overdose of the drug resulted in multiple deaths in the U.S between 1999 and 2014.
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When opioids are taken in excess, they cause severe blockage in the parts of the brain & body where there are increased concentrations of opioid receptors. Examples of these high-density regions include the brainstem, spinal cord, and the limbic system. The brainstem is made up of the medulla, which controls the body’s autonomous, involuntary functions like breathing and heartbeat. When an overdose occurs, parts of the brain containing high concentrations of opioid receptors get depressed, causing respiratory and heart failure.
People who use opioids on a frequent basis are more likely to become dependent on the product, and once addicted, they may find it really difficult to stop taking it. The CDC found that nearly 1 in every four patients undergoing long-term opioid therapy struggles with addiction.
CBD Oil: How It Works
Cannabis contains cannabinoids (CBD), which bind on the brain’s cannabinoid receptors to regulate the communication between cells. The basal ganglia, cerebellum, and the hippocampus are areas of the brain featuring the highest densities of cannabinoid receptors. They’re responsible for handling various functions, including emotions, motor control, and memory. In the event of an overdose, side effects might include a headache, paranoia, nausea, and vomiting, but fortunately, there has been no reported case of death caused by CBD overdose.
Why Go For Cannabis For Pain Treatment?
While both CBD oil and opioids are highly effective in relieving pain, CBD-based products have never been associated with death due to overdose, while the CDC claims that there are 3 in every five overdose deaths involving an opioid. So why utilize opioids to treat your pain? The legal acceptance and widespread availability of opioids make them easier to find and use. Classified as schedule II medications by DEA, some opioids can be sold and prescribed to you by healthcare professionals. CBD, on the other hand, is classified as a schedule I drug, making it illegal federally, though it doesn’t cause the “high effect”.
This means that, despite their incredible medical value (like treating pain, fibromyalgia, and epilepsy), some states still perceive CBD oil as an illegal product.